Background: The 39 item Parkinson’s disease questionnaire (PDQ-39) is the most widely used patient reported rating scale in Parkinson’s disease. However, several fundamental measurement assumptions ...

Department of Neurology and Alzheimer Center, Vrije Universiteit Medical Center, Amsterdam, the Netherlands Correspondence to: W M van der Flier Department of Neurology and Alzheimer Center, Vrije ...

2 National Center for Neurological Disorders, Shanghai, People's Republic of China Correspondence to Chao Quan, Department of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University; ...

Objective To characterise the topographic patterns of thalamic infarcts associated with various stroke syndromes and aetiologies. Methods In this study, 168 consecutive patients with acute infarcts ...

4 Department of Pathology, College of Medicine, University of Florida, Gainesville, Florida, USA Correspondence to Dr Tetsuo Ashizawa, Department of Neurology, College of Medicine, University of ...

Prospective population based-registers of amyotrophic lateral sclerosis (ALS) have operated in Europe for over two decades, and have provided important insights into our understanding of ALS. Here, we ...

Background Deutetrabenazine (SD-809) is a novel deuterium containing VMAT2 inhibitor. When deuterium, a naturally occurring form of hydrogen, is at specific sites, in this case CYP2D6 enzymatic ...

OBJECTIVES To evaluate neuromuscular signs and symptoms in patients with newly diagnosed hypothyroidism and hyperthyroidism. METHODS A prospective cohort study was performed in adult patients with ...

Background The phosphorylated neurofilament heavy subunit (pNF-H), a major structural component of motor axons, is a promising putative biomarker in amyotrophic lateral sclerosis (ALS) but has been ...

Dr Jean-Yves Delattre, Service de Neurologie, Hôpital de la Salpêtrière, 47 Boulevard de l'Hôpital, 75651 Paris Cedex 13, France OBJECTIVES To evaluate the effect of a combination of immunoglobulins ...

a Department of Medicine, Faculty of Medicine, b Department of Biostatistics and Demography, Faculty of Public Health, Khon Kaen University, Khon Kaen, 40002 Thailand Dr Suthipun Jitpimolmard, ...

Background and objectives: Hyperekplexia and the stiff-man syndrome (SMS) are both conditions with exaggerated startle suggesting abnormal brainstem function. Investigation of brainstem reflexes may ...