Notre Dame and Penn State are set for the College Football Playoff Orange Bowl semifinal with a shot at the national title matchup on the line. Here’s the latest prediction for the game from an expert analytical model that projects scores and picks winners.

The sixth-seeded Nittany Lions will face their toughest challenge in the College Football Playoff against the seventh-seeded Fighting Irish on Thursday (7:30 p.m., ESPN).

Either the Irish or the Nittany Lions will look to book a trip to the Jan. 20 CFP national championship game at Mercedes-Benz Stadium in Atlanta.