The Chicago Cubs (60-42) visit the South Side of Chicago to face the Chicago White Sox (37-66) Friday in the first game of a 3-game interleague series. First pitch from Rate Field is at 7:40 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Cubs vs. White Sox odds and make our expert MLB picks and predictions for the best bets.

Chicago Cubs rookie Cade Horton Horton left Sunday’s game in the sixth inning with a 1-0 lead, but the Cubs lost 6-1. It was Horton’s fourth no-decision of the season.

BOTTOM LINE: The Chicago Cubs lead 1-0 in a three-game series with the Boston Red Sox. Chicago is 31-16 at home and 58-39 overall. The Cubs have a 44-7 record in games when they out-hit their opponents.