DJ-1 is a protein with wide subcellular distribution and pleiotropic functions. The loss-of-function mutations of DJ-1 are associated with autosomal recessive early-onset Parkinson's disease yet the ...

The secretory pathway comprising the ER, Golgi apparatus and plasma membrane is central in the growth and development of the eukaryotic cell. Membrane-bound and soluble molecules that are destined for ...

FRANKFURT. A tangle of pockets, tubes and sac-like membrane structures runs through the cells of humans, animals, plants and fungi: the endoplasmic reticulum, or ER for short. In the ER, proteins are ...

Aging involves a balance between oxidants and antioxidants, low-grade inflammation and a protein response that occurs at the cellular level, which is responsible for many health disorders. Exercise ...

The involvement of myosin XI in generating the motive force for cytoplasmic streaming in plant cells is becoming evident. For a comprehensive understanding of the physiological roles of myosin XI ...

PhD defence: Tangled yet in tune: Orchestrating the dynamics of microtubules, vimentin and endoplasmic reticulum PLEASE NOTE: If a candidate gives a layman's talk, the livestream will start fifteen ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, No. 39 (September 29, 2015), pp. 12205-12210 (6 pages) Endoplasmic reticulum (ER)-associated degradation ...

HGS-ETR1, an antibody targeting TRAIL-R1, in combination with paclitaxel and carboplatin in patients with advanced solid malignancies: Results of a phase 1 and PK study Ca++ mobilization leading to ...

Drugs are metabolized in the liver using several enzyme-catalyzed processes. These enzymes are collectively referred to as the hepatic microsomal enzyme system, and they are usually present in the ...