Generative AI predicts and assembles cell drug responses like Lego blocks

Controlling the state of a cell in a desired direction is one of the central challenges in life sciences, including drug ...
IEEE

DBNX: A Machine Learning Method for Ensembling Polygenic Risk Scores and Non-Genetic Factors

Abstract: Polygenic risk scoring (PRS) holds promise for improving disease prediction and medical treatments by evaluating an individual’s genetic susceptibility through multiple genetic variants.
The American Journal of Managed Care

Novel Machine Learning Model Improves MASLD Detection in Type 2 Diabetes

A machine learning–driven web tool based on 13 standard patient metrics demonstrates strong predictive performance for MASLD, ...
eLife

A recursive pathway for isoleucine biosynthesis arises from enzyme promiscuity

The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens Lyngby, Denmark ...
InfoWorld

7 newer data science tools you should be using with Python

Already using NumPy, Pandas, and Scikit-learn? Here are seven more powerful data wrangling tools that deserve a place in your ...
eLife

Explainable machine learning-assisted exploration of chromatin dynamics reveals chromosome-specific response to serum starvation

This interesting study adapts machine learning tools to analyze movements of a chromatin locus in living cells in response to serum starvation. The machine learning approach developed is useful, the ...
Frontiers

Machine learning–derived genetic risk scores identify IL21 as a predictor of response to omalizumab and dupilumab in asthma

Rationale: Genetic risk scores (GRS) of Th1/2/17-related loci may be associated with response to biologics. We leveraged previously published machine learning-derived GRSs associated with plasma ...
The Conversation

A new treatment for Huntington’s disease is genuinely promising – but here’s why we still need caution

Bryce Vissel does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their ...
Medical Xpress

Genetic adaptation helps Turkana people conserve water in harsh desert climate

Cornell researchers have contributed to a multi-institutional study of how the nomadic Turkana people of northern Kenya—who have lived for thousands of years in extreme desert conditions—evolved to ...
The Lancet

Development of a multi-task deep learning system for classification of nine common knee abnormalities on MRI: a large-scale, multicentre, stepwise validation study

aDepartment of Radiology, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China bInstitute of High-End Intelligent Health Equipment, Academy of Orthopedics, Guangdong Province ...