He Yuan, Mou Qiang, He Yubing, Zhao Xiaoyan, Wang Jian, Zhou Guomin, Zhang Jianhua ...

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the ...

Successes of protein science during the past century have provided a high level of understanding of the relationships between the protein structure and ...

This fully updated volume explores a wide array of new and state-of-the-art tools and resources for protein function prediction. Beginning with in-depth overviews of essential underlying computational ...

A new study presents computational strategies to manipulate membrane protein folding and function for biotechnological applications.

Cryo-electron microscopy and tomography are transforming structural biology, offering unprecedented insights into ...

Physics-based ML framework designs IDPs—biomolecules without fixed structures that underlie key functions and diseases such as Parkinson’s.

In recent years, the study of protein structure and dynamics has undergone a profound transformation. The integration of advanced biophysical techniques, ...

A biochemical and bioinformatics approach shows how T6SS immunity proteins bind to and neutralize a range of non-cognate effectors, which is critical for promoting bacterial fitness in mixed-strain ...