New research shows that curium — one of the heaviest known elements — can be manipulated to a larger degree than previously thought. An international team published a study on July 15 in the journal ...

One class of drugs that has shown promise in treating diseases ranging from lung cancer to COVID-19 is targeted covalent inhibitors (TCIs). These small molecule drugs form covalent bonds with their ...

Prior to 2000, many drugs that formed a covalent bond with targets did so non-selectively, which often led to undesired side effects when compared to non-covalent drugs. This led to the belief that ...

One of the key challenges in chemistry is to break and form bonds selectively in complex organic molecules that possess a range of different functional groups. To do this at the single-molecule level ...

Researchers at Baylor College of Medicine have developed a powerful new data analysis method named COOKIE-Pro (Covalent ...

Matchpoint Therapeutics has publicly launched with $70 million in series A financing and an earlier $30 million in seed money to develop covalent drugs for immune diseases. Its founders include ...