Discover the complete list of Nobel Prize in Medicine winners from 1901 to 2025. Explore year-wise laureates, their groundbreaking discoveries, and how each contribution transformed healthcare.

How are sugars attached to proteins? Sugars are commonly attached to proteins in a process called glycosylation. This fascinating modification involves linking sugar molecules to specific amino acids ...

In the secretory pathway, the pH within organelles is gradually acidified, starting at 7.1 to 7.2 in the endoplasmic reticulum, decreasing to 6.0 to 6.7 in the Golgi apparatus/trans-Golgi network ...

The zebrafish fat-free (ffr) mutation was identified in a physiological screen for genes that regulate lipid metabolism. ffr mutant larvae are morphologically indistinguishable from wild-type sibling ...

In her new book, “The Ideological Brain,” the neuroscientist Leor Zmigrod outlines what makes some people prone to rigid thinking. “Ideologies numb our direct experience of the world,” Leor Zmigrod, a ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. This work by the Meng ...

The Golgi apparatus modifies, sorts and packages proteins to be sent to their final destinations, whether that's within or outside of the cell. It's a core function, but little studied in the setting ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Lipidated ATG8/LC3 proteins are recruited to ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The degradation of organelles by autophagy is ...

The Golgi apparatus plays a crucial role in lysosome biogenesis and the delivery of lysosomal enzymes, essential for maintaining cellular homeostasis and ensuring cell survival. Deficiencies in Golgi ...