The San Francisco 49ers will likely part ways with at least one key member from the core of their teams that went to two Super Bowls and four NFC championship games in five years. The 49ers are expected to trade wide receiver Deebo Samuel this offseason and fullback Kyle Juszczyk could become a cap casualty as the team looks to rebound from a disappointing 6-11 season in 2024 and retool to become contenders again.