GLP-1–pathway agonists such as semaglutide and newer multi-agonists have transformed care for obesity and diabetes, yet developers still wrestle with durability, tissue targeting, and signal "bias." ...

Aging, neurological diseases and our bodies' stress response are all linked to the tiny power plants inside each cell known as mitochondria. To function properly, mitochondria must first read ...

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood. Currently ...

Opening up about his inspiration for the upcoming animation, Smurfs director Chris Miller wanted to “honour the DNA of the original comics” with his take on the creatures. Barack Obama responds to ...

Smurfs director Chris Miller wanted to “honour the DNA of the original comics” with his upcoming animated feature film on the creatures. The movie – which will feature Rihanna as the voice of ...

To many working biologists, DNA-modifying enzymes are tools, not unlike a pair of molecule-sized scissors. To Dr. Barry Stoddard, a professor in the Basic Sciences division at Fred Hutch, these ...

Cutting-edge gene editing technology could eradicate Down syndrome, according to Japanese scientists. Down syndrome, which causes a range of developmental differences and affects 1 in 700 newborns in ...

The one-off treatment highlights the promise of a new type of gene editing and the challenges of using it to treat extremely rare genetic diseases. Doctors say they constructed a bespoke gene-editing ...

According to a former White House official for Bush, the US federal government has secretly spent trillions building doomsday bunkers to house the rich and powerful. Fitts, who also made many wild ...