C&EN

MD-4251: A First-in-Class Oral MDM2 Degrader Inducing Complete Tumor Regression with Single-Dose Administration

Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, Michigan 48109, United States ...
C&EN

Discovery and Characterization of a First-in-Class LIV1-TLR7/8 Immunomodulatory Conjugate with Robust Myeloid Activation and Antitumor Activity

Bristol Myers Squibb Research & Development, 700 Bay Road, Redwood City, California 94063, United States ...
Motor Trend

2025 Mercedes-Benz CLE-Class Cabriolet First Drive: Expectations Fulfilled

For those unfamiliar, the Mercedes CLE is a replacement for both the C-Class and E-Class coupes and convertibles. Shrinking of the segment prompted Benz to blend the two-door Cs and Es into one car ...
Frontiers

Development of the teacher’s technological pedagogical content knowledge (TPACK) from the Lesson Study: A systematic review

1 Faculty of Educational Sciences, Universidad del Magdalena, Santa Marta, Colombia 2 Department of Didactics and Educational Organization, Faculty of Educational Sciences, University of Seville, ...