Nobel laureate Shimon Sakaguchi reflects on the role of regulatory T cells in peripheral immune tolerance and how the cells ...

Immune Cell Transporters as Mediators of Renal and Vascular Dysfunction and blood pressure Immune cells - including macrophages, ...

By examining genomic variation more closely, scientists can now identify new disease connections with greater speed and accuracy. For centuries, scientists have recognized that certain illnesses can ...

Scientists have developed a highly sensitive single-cell tool that can help uncover links to complex diseases. Known as ...

Regulatory T cells, which prevent the immune system from attacking the body, were the subject of this year’s Physiology or ...

The deadliest type of brain cancer does something doctors didn't expect: it thins the skull. New research shows glioblastoma goes beyond just attacking the brain; it also weakens the bone protecting ...

An overview of how genetics associated with schizophrenia and bipolar can influence how cells communicate, ultimately ...

During a live event, Ann F. Mohrbacher, MD, discussed outcomes from the latest follow-up of the ZUMA-7 and TRANSFORM trials.

DuoCAR20.19.22-D95 targets CD19, CD20, and CD22, addressing antigen escape in B-cell malignancies like B-ALL and B-NHL. Early-stage trials show no safety concerns for DuoCAR20.19.22-D95, with ongoing ...

Introduction: The exhaustion of chimeric antigen receptor T cells (CAR-T) hampers the efficacy of CAR-T cell therapy. Persistent antigen stimulation in T cells results in a surge of intracellular ...

NEW YORK – The US Food and Drug Administration has granted Singapore-based Lion TCR permission to begin a Phase Ib/II trial for a T-cell receptor (TCR) T-cell therapy, LioCyx-M004, in patients with ...