In this important work, the authors present a new transformer-based neural network designed to isolate and quantify higher-order epistasis in protein sequences. They provide solid evidence that higher ...

Researchers have found that nearly three-quarters of the population carry newly identified genetic elements called Inocles, ...

Research indicates that discussions, debates, and studies in the 19th and 20th centuries explored personal agency and ...

Positive Phase 1 study showed safety, tolerability and a linear pharmacokinetic: pharmacodynamic: efficacy relationship (1: 1: 1)Planning ...

Drawing on lessons learned, advocates should remain focused on three things for implementation: ensuring it is easy for taxpayers to contribute to scholarship-granting organizations, for ...

BACKGROUND: PYGM (muscle glycogen phosphorylase), the rate-limiting enzyme in glycogenolysis, plays an indispensable role in maintaining cardiac energy metabolism. However, the role of PYGM in the ...

This is the first of a two-part article that examines both structural and processural paradigms of social theory. This argues that the structural-based theories cannot do what they claim to do; in ...

People with Chagas disease appear to face a greater risk of cognitive difficulties, including memory and spatial problems, compared to those with other forms of heart failure. A new study published in ...

This valuable study analyzes aging-related chromatin changes through the lens of intra-chromosomal gene correlation length, which is a novel computational metric that captures spatial correlations in ...

OCALIVA received FDA accelerated approval in 2016 for the treatment of PBC in adults with an inadequate response to or intolerance of ursodeoxycholic acid (UDCA). Since then, OCALIVA has played a ...

We’re increasingly developing bonds with chatbots. While that’s safe for some, it’s dangerous for others.