Lasso peptides are natural products made by bacteria. To produce these peptides, bacteria use ribosomes to build chains of ...

In the hunt for new therapeutics for cancer and infectious diseases, lasso peptides prove to be a catch. Their knot-like structures afford these molecules high stability and diverse biological ...

Chemistry researchers at the University of Utah have uncovered an enzyme, dubbed PapB, that can "tie off" therapeutic ...

In the hunt for new therapeutics for cancer and infectious diseases, lasso peptides prove to be a catch. Their knot-like ...

The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens Lyngby, Denmark ...

A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...

GLP-1–pathway agonists such as semaglutide and newer multi-agonists have transformed care for obesity and diabetes, yet developers still wrestle with durability, tissue targeting, and signal "bias." ...

Peroxidases are enzymes that break down hydrogen peroxide in organisms. Since their discovery in 1998, the electron source of ...

A team led by Prof. YIN Heng from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences identified the key glycosyltransferase that catalyzes the conversion of Reb D to Reb M, ...