Developed through a collaboration between the University of Texas at Austin and pharmaceutical company Sanofi, the tool could ...
A combination of cryogenic electron microscopy and molecular simulations has been used to study the structure and dynamics of an enzyme called ACE.
In this important work, the authors present a new transformer-based neural network designed to isolate and quantify higher-order epistasis in protein sequences. They provide solid evidence that higher ...
Honeysuckle nanovesicles reduced gut inflammation and restored microbial and immune balance in colitis models, suggesting a microbiota-based therapy.
Live Science on MSN
How the body changes in space — usually, for the worse
From causing muscle loss to raising the risk of blood clots, long-haul space missions can have a profound impact on the human ...
Researchers created a stable way to analyze membrane proteins with SPR, solving a major technical barrier and improving ...
To solve a problem, scientists first need to see it clearly. Whether it’s a virus slipping past the immune system or plaques ...
The protein homeostasis (proteostasis) network (Balch et al, 2008), consisting of a collection of molecular chaperones, ...
If future studies confirm the rescued receptors work normally, the study offers a new roadmap for rare disease drug development.
6don MSN
Single drug provides first evidence of 'nearly universal' pharmacological chaperone for rare disease
A study published in Nature Structural & Molecular Biology is the first time researchers have shown evidence that a single ...
SciSparc Ltd. (Nasdaq: SPRC) (the "Company" or "SciSparc"), a specialty clinical-stage pharmaceutical company focusing on the ...
2don MSN
Unfolded protein response pathway offers new targets to treat bone weakness in cancer patients
Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate ...
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