In this important work, the authors present a new transformer-based neural network designed to isolate and quantify higher-order epistasis in protein sequences. They provide solid evidence that higher ...
Recent advances in high-throughput microbiome profiling have generated expansive data sets that offer unprecedented ...
We thank Dr. Jianzhi Zhang, Dr. Xionglei He, Dr. Weiwei Zhai, Shanshan Chen, Han Liu, Tianhan Wang, and three anonymous reviewers for valuable comments. This work was supported by the Strategic ...
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Genetics research in Parkinson's disease has identified over 100 risk loci, yet translating these findings into understanding of disease mechanisms, clinical and pathological heterogeneity, and ...
Abstract: We show that the augmented primal-dual gradient algorithms can achieve global exponential convergence with partially strongly convex functions. In particular, the objective function only ...
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This work is a important resource for hypothesis testing of candidate upstream transcriptional regulatory factors that control the spatiotemporal expression of selector genes and their targets for ...
Viral infections pose a major threat to global health, causing severe pneumonia, meningitis, hepatitis, and fatal complications. Viruses are highly dependent on host cellular factors to complete their ...
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