Some cells, such as immune cells, are highly mobile—they constantly remodel their shape, migrate toward a wound that needs to ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

INVESTING into fitness is one of the best commitments you can make for yourself—whether that means putting in hours at the gym, carving time for recovery, or simply finding smarter ways to support ...

When we think about the heart, we imagine the organ in our chest that keeps us alive. But did you know your legs, more specifically your calf muscles, have a heart-like function as well? Experts often ...

Skeletal muscle tissue has the largest mass in the human body, accounting for 45% of the total weight. Muscle injuries can be caused by bruising, stretching or laceration. The current classification ...

Abstract: In this paper, an existing physiological muscle model that predicts muscular force in response to electrical stimulation is adapted to be compatible with gradient-based optimization, in ...

New research has identified the enzyme glutamate dehydrogenase 1 (GLUD1) as a new therapeutic target for Duchenne muscular dystrophy (DMD). In preclinical DMD mouse models, investigators demonstrated ...

Tomohiro Yasuda, William F. Brechue, Taku Fujita, Yoshiaki Sato, Takashi Abe. (2008) Muscle Activation During Low-Intensity Muscle Contractions With Varying Levels of External Limb Compression.

Dystonia is a neurological disorder causing involuntary muscle contractions and abnormal postures. Botulinum toxin (e.g., Botox) is the gold-standard, first-line treatment for focal dystonias, which ...

Your muscles aren’t just for lifting heavy objects and looking good in photos—they’re actually functioning as a sophisticated chemical factory that produces brain-boosting compounds essential for ...

Interim data showed 110% average microdystrophin expression and up to 88% dystrophin-positive muscle fibers in the first three participants. Two patients saw an 8% average heart function improvement ...