Multiple regression equations designed to explain or predict should be validated. This tutorial shows how recalculation of the coefficient of determination on hold-out sample data or new sample data ...

In a typical randomized clinical trial, a continuous variable of interest (e.g., bone density) is measured at baseline and fixed postbaseline time points. The resulting longitudinal data, often ...

Genome-wide association studies have been successful in identifying genes and pathways involved in the development of human complex traits and diseases 1,2. For many traits, such as height and BMI, ...