Kate Adamala started work on a cell in which the natural molecular structure is reversed. Then a possible doomsday scenario became clear.

A massively parallel reporter assay quantifies the translational consequence of over one million 5’UTR variants.

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

The president does not have the power to unilaterally change voting laws, and any executive order regarding elections is likely to see immediate legal challenges. By Tyler Pager and Nick Corasaniti ...

Scientists at the University of Pittsburgh, together with colleagues at the University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute, have identified how a long ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Nuclease-free water (catalog no. 96370) and urea (catalog no.

Ischemic heart disease remains a major global health challenge, with myocardial ischemia-reperfusion injury (MIRI) being one of its most common and severe pathophysiological complications. The ...

Ferroptosis is an iron-dependent programmed death caused by the imbalance of lipid peroxides in cells. Unlike apoptosis, autophagy and necrosis, ferroptosis is mainly induced by the small molecule ...

A new review article published in Genes & Diseases explores the intricate relationship between non-coding RNAs and oxidative stress in cancer progression shedding new light on the mechanisms that ...

A research team has identified NEAT1, a long non-coding RNA, as a key player in DNA repair. This discovery links RNA metabolism to genome stability and opens up potential new cancer treatments. Credit ...