Research reveals that δ-receptor agonists like KNT-127 alleviate IBS symptoms by modulating gut-brain interactions and ...

Vistagen (Nasdaq: VTGN), a clinical-stage biopharmaceutical company pioneering neuroscience to deliver groundbreaking therapies for individuals affected by psychiatric and neurological disorders, ...

Prenatal exposure to neuroinflammation (cytokines) may provide a biomarker for the risk of later development of Alzheimer's ...

A dysfunctional signaling pathway in the hippocampus has been linked to chronic pain-related memory impairment in mice.

hyperalgesia, reduced social behaviors and cognitive deficits,” including memory deficits (Hein and O’Banion, 2009, page 2). Since memory loss is closely associated with both AD and ...

On 4 September, she defended her dissertation, titled "Nocebo Hyperalgesia and Pain Progression: Prediction, Acquisition, and Recovery." Both the healthy women and those with fibromyalgia were ...

Researchers from Vera Salus Ricerca Srl and affiliated organizations have reported the discovery and preclinical characterization of novel sigma-1 receptor (S1R) antagonists as potential new analgesic ...

The Central Nervous System and Pain Perception The central nervous system (CNS), comprising the brain and spinal cord, plays a crucial role in how the body perceives pain. Under normal circumstances, ...

Conclusions The development of oesophageal hyperalgesia is prevented by physiologically increasing parasympathetic tone. This effect is pharmacologically blocked with atropine, providing evidence that ...

When glutamate is too high and GABA levels are too low, as is the case with fibromyalgia and ME/CFS, symptoms like hyperalgesia (heightened sensitivity to pain), anxiety, restlessness, brain fog, ...

An abnormal LBT was found in all patients with fibromyalgia in comparison with the IBS group. Although it is likely that endotoxin produces hyperalgesia, the common presence of bacterial overgrowth in ...

Postoperatively, the patient encountered multiple complications, including recurrence of BI, FTT, constipation, dysautonomia, visceral hyperalgesia and neurogenic bladder, necessitating specific ...