BACKGROUND: Alternative splicing plays crucial roles in normal heart development and cardiac disease by influencing protein-coding sequences, functional domains, and molecular networks. However, a ...

The death of William (Bill) Rutter at the grand old age of 97 in July reminded me to remember not only him, but several of the other pioneers of our industry—lest we should forget them.

A new randomized study finds that a lab test that reads tumor genes can identify which patients with recurrent prostate ...

Pharmacogenomic testing can tell how a drug is likely to work in a certain person. But is it ready for rolling out to the ...

Doctors can order genetic tests for people at high risk of breast cancer, and insurance often covers those, Kamal says. For ...

Matthew Taylor likened his recently published work alongside doctoral student Gary Dunn to kicking over a rock. Once the ...

It's no secret that we need new ways to treat and detect disease, including cancer. Specifically, we need better biomarkers ...

This important study identifies a putative iron and zinc transporter in the plasma membrane of the obligate intracellular pathogen, Toxoplasma gondii. Using an array of different approaches, the ...

How cell and gene therapy developers can lessen the chances of receiving FDA complete response letters through the use of ...

Myc dysregulation in activated macrophages impairs antioxidant defenses, locking them in a vicious cycle that amplifies type I interferon signaling, driving hyperinflammation and immunosuppression.