How enzymes 'dance' while they work, and why that's important

Researchers from Tokyo Metropolitan University have developed a new structure determination method using nuclear magnetic resonance (NMR) spectroscopy which shows how different parts of complex ...
News-Medical.Net

New NMR technique reveals atomic-scale motion in catalytic enzyme function

Researchers from Tokyo Metropolitan University have developed a new structure determination method using Nuclear Magnetic Resonance (NMR) spectroscopy which shows how different parts of complex ...
Nanowerk

Scientists glimpse how enzymes 'dance' while they work, and why that's important

Focusing on an enzyme in yeast, they demonstrated how contrasts in atomic scale motions impact their function. The method promises unprecedented access to the mechanisms by which biomolecules work, ...
Science Daily

This “chaos enzyme” may hold the key to stopping cancer spread

A Weill Cornell Medicine team has found that triple-negative breast cancer depends on the enzyme EZH2 to spread. By silencing key genes, EZH2 drives chaotic cell divisions and fuels metastasis.
C&EN

Catalytic Residue Reprogramming Enhances Enzyme Activity at Alkaline pH via Phenolate-Mediated Proton Transfer

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Directed evolution offers a complementary strategy by ...
earth

Humans inherited genes from Neanderthals that still limit our muscle activity

Most of us carry a small trace of Neanderthal ancestry and, in some cases, that legacy sits in our legs. A single change in a muscle enzyme can subtly throttle how hard muscles can work under pressure ...
IEEE

A Graph Neural Network-Based Dual Attention Fusion Network for CSI-based Activity Recognition

Abstract: Over the past decade, Channel State Information (CSI)-based human activity recognition (HAR) has attracted wide attention. Despite significant advancements, existing CSI-based HAR methods ...
pna

PH, US military forces conduct 8th Maritime Cooperative Activity

NAVAL FORMATION. (Front to back) Guided missile frigate BRP Miguel Malvar (FFG-06), Coast Guard patrol vessels BRP Cabra (MRRV-4409) and BRP Suluan (MRRV-4406), and US guided missile destroyer USS ...
News Medical

Targeting a key enzyme could reverse early Parkinson's effects

Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a single genetic mutation, according to a new Stanford Medicine-led study ...
IEEE

Robust Skeletal-Graph Reconstruction Using mmWave Radar and its Application for Human-Activity Recognition

Abstract: Skeletal graphs can represent concise and reliable features for human-activity recognition in recent years. However, they have to be acquired by Kinect sensors or regular cameras, which rely ...
C&EN

Membrane Transport Modulates the pH-Regulated Feedback of an Enzyme Reaction Confined within Lipid Vesicles

School of Chemistry, University of Leeds, Leeds LS2 9JT, U.K. Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, U.K. School of Chemistry, University of Leeds, Leeds ...
pna

7th PH maritime cooperative activity with US, Canada on – Brawner

MANILA – Naval and air units of the Philippines, Canada, and the United States are conducting the 7th Multilateral Maritime Cooperative Activity (MMCA) in the country's exclusive economic zone (EEZ).