eLife

Importance of higher-order epistasis in protein sequence-function relationships

In this important work, the authors present a new transformer-based neural network designed to isolate and quantify higher-order epistasis in protein sequences. They provide solid evidence that higher ...
IEEE

A Backward Algorithm to Determine the Existence of Legal Firing Sequences in Ordinary Petri Nets

Abstract: Petri nets (PNs) are a graphical and mathematical tool to model various event-driven automated systems. Reachability is a fundamental property of PNs. The existence of a non-negative integer ...
IEEE

Robust Electrical Impedance Tomography for Respiratory Monitoring

Abstract: Thoracic electrical impedance tomography (EIT) is a crucial bedside monitoring tool, particularly valuable in pulmonary and critical care medicine. However, its routine clinical application ...
PNAS

Distribution of centrality measures on undirected random networks via the cavity method

Centrality measures allow to identify important nodes in networked systems. An open question in network theory is the empirical observation that a node’s centrality—whose computation requires ...
C&EN

Sequence Divergence in the Arginase Domain of Ornithine Decarboxylase/Arginase in Fusobacteriacea Leads to Loss of Function in Oral Associated Species

Department of Chemistry, University of British Columbia, Okanagan Campus, 3247 University Way, Kelowna V1V 1V7, Canada ...
PNAS

A single Mid-Pleistocene long-distance dispersal by a bird can explain the extreme bipolar disjunction in crowberries (Empetrum)

Edited by Peter H. Raven, Missouri Botanical Garden, St. Louis, MO, and approved February 17, 2011 (received for review August 18, 2010) ...