CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR ...
The clinical success of CRISPR-based treatments is fundamentally dependent on sophisticated gRNA targeting systems that ...
CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...
Optimized approach for universal chromosomal DNA rearrangements achieves as high as 20% insertion efficiency, mobilizing genomic DNA at the megabase scale.
Ribonucleic acid, also called RNA, is a molecule present in all living cells. It plays a critical role in transmitting genetic instructions from DNA and creating proteins. With the power to execute a ...
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Bridge recombinases, optimized for human cells, enable massive programmable DNA rearrangements
For decades, gene-editing science has been limited to making small, precise edits to human DNA, akin to correcting typos in ...
Scientists are exploring how RNA might have jump-started life four billion years ago and how it's now advancing drug ...
The investment from Brown parents Giammaria and Sabrina Giuliani will support scholars seeking to unlock the potential of RNA ...
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Triggering RNA activation on demand: Strategy expands options for therapeutics and gene editing
National University of Singapore (NUS) researchers have devised a method to safely and temporarily "switch off" and then "turn on" ribonucleic acid (RNA) inside cells. This is achieved using ...
Biologists have discovered that disruptions in transfer RNA function can lead to the development of cleft lip and cleft palate. Cleft lip and cleft palate are among the most common birth defects, ...
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