In the first study, the researchers sequenced tumors from more than 14,000 people, and found that 17.1% contained ecDNA, with prevalence varying depending on a cancer’s tissue of origin. Advanced and ...
For decades, scientists have known that bacteria can exchange genetic material, in a process called horizontal gene transfer.
Despite the diversity inherent to cancer, they all share a common theme: many things tend to go wrong. This can make it difficult to understand which factors are driving the cancer and which ones are ...
A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA -- loops of DNA found outside of regular chromosomes -- are twice as ...
SAN DIEGO--(BUSINESS WIRE)--Boundless Bio, a clinical stage, next-generation precision oncology company interrogating extrachromosomal DNA (ecDNA) biology to deliver transformative therapies to ...
An international team of scientists has revealed how rogue rings of DNA that float outside of our chromosomes—known as extrachromosomal DNA, or ecDNA—can drive the growth of a large proportion of ...
Now, researchers from UC San Diego and their colleagues have found that HPV DNA hybridizes with human DNA genes in oropharyngeal cancer cells, forming extrachromosomal circular DNA (ecDNA) that ...
There is usually one bit of genomic DNA in a bacterial cell that encodes for most of its functions, but bacteria can carry other bits of genetic material like plasmids, which could carry a gene for ...
Researchers including those at the University of Tokyo have made a surprising discovery hiding in people's mouths: Inocles, giant DNA elements that had previously escaped detection. These appear to ...