AZoLifeSciences on MSN
RyR1-Mediated CICR Plays Minimal Role in Normal Skeletal Muscle Contraction
Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release.
18don MSN
Genetic model reveals a form of calcium release is unnecessary for normal muscle contraction
The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...
The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium ...
Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...
The clitoris is a vital part of the female sexual system, playing a crucial role in sexual satisfaction and overall sexual health. During arousal, the smooth muscle within the corpus cavernosum of the ...
A research group led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, has ...
The contractile responses of esophageal smooth muscle (SM) induced by platelet-activating factor (PAF) involve the activation of L-type voltage-dependent calcium channels (L-type VDCCs), ...
Mechanically Matched Heart-on-a-Chip Platform Mediated Maturation of Excitation–Contraction Coupling
School of Mechanical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China Shandong Institute of Mechanical Design and Research, Jinan 250353, China School of ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Dynamic changes in the arrangement of ...
We are grateful for Dr. Mai Kanai (The Jikei University), Ikue Hiraga (Juntendo University), and the Laboratories of Molecular and Biochemical Research, Research Support Center (Juntendo University), ...
Dr. Achilles “Oggie” Pappano of West Simsbury, CT, died peacefully on Tuesday, December 31, 2024, at UConn John Dempsey Hospital, surrounded by his high school sweetheart and wife of 61 years, Mary ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback