Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D ...
Scientists studying tiny roundworms have uncovered how the secrets of a long life can be passed from parents to their ...
ABSTRACT: Introduction: Radiation pulmonary injury (RPI) is a prevalent complication in scenarios such as nuclear radiation disaster accidents, nuclear terror events ...
HHMI Janelia Research Campus Senior Group Leader Meng Wang and her team study longevity. They've shown that by overexpressing ...
Post-translational modifications (PTMs) act as pivotal molecular hubs integrating heat stress signals into cellular responses driving heat-related diseases like heatstroke. This review synthesizes ...
New in vitro results show Telomir-1 adds KDM5 family inhibition to its previously reported KDM2/KDM6 and DNA methylation activity, potentially representing a novel frontier in epigenetic therapy where ...
Cancer and aging are driven in part by the silencing of protective genes that regulate cell growth, repair, and survival. When these genes are inactive, cells lose critical defenses, enabling tumors ...
Metabolic reprogramming and epigenetic modification have been widely observed in cancer research. Based on accumulating experimental evidence in recent years, beginning with metabolic reprogramming ...
This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...
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