Genes enriched in the phenylpropanoid biosynthesis pathway are regulated by histone modification.

This mechanism for conferring longevity across generations could also explain how other stress-adaptive traits are passed to offspring.

The serine 31 (Ser31) phosphorylation modification (H3.3S31ph) in the N-terminal tail of the histone variant H3.3 can ...

Aging is inevitable, but how fast your cells age isn't set in stone. On a molecular level, biological age is measured using something called the epigenetic clock, which isn't tied to chronological age ...

Hepatocellular carcinoma (HCC) is the second leading cause of cancer death worldwide, largely due to the limited efficacy of ...

Cardiovascular aging is a major contributor to the global burden of heart disease, characterized by structural remodeling, metabolic alterations, and a ...

Introduction Chronic caregiving stress accelerates biological aging, reflecting disease risk and mortality; however, the ...

Neurons are highly specialized cells, and their proper functioning depends on preserving their identity throughout life. A team of researchers has identified that two enzymes, KDM1A and KDM5C, ...

Drug repurposing screens reveal several epigenetic inhibitors as active against P. vivax hypnozoites demonstrating that epigenetic pathways play a central role in hypnozoite quiescence.