The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release.

BACKGROUND: Alternative splicing plays crucial roles in normal heart development and cardiac disease by influencing protein-coding sequences, functional domains, and molecular networks. However, a ...

Fibronectin triggers secretion of extracellular vesicles carrying collagen VI that regulate smooth muscle cell adhesion and migration during vascular repair and atherogenesis.

BACKGROUND: PYGM (muscle glycogen phosphorylase), the rate-limiting enzyme in glycogenolysis, plays an indispensable role in maintaining cardiac energy metabolism. However, the role of PYGM in the ...

Accumulating evidence has made it clear that not only does the renin–angiotensin–aldosterone system (RAAS) exist in the circulation where it is driven by renal renin, but it is also active in many ...

Muscle tissues, comprising skeletal and cardiac types, play a pivotal role in numerous biochemical, mechanical, and physiological functions. Beyond their fundamental role in movement and force ...

We list the best payment gateways, to make it simple and easy for businesses to securely handle card payments online and in person. Payment gateways offer the flexibility of being able to take card ...