When these kissing loops were disrupted by manipulating the building blocks of MEG3, the tumor suppression function of MEG3 was also disrupted. The findings of the group might have wider ...

Negative feedback loops help maintain the function of mutated proteins Date: June 23, 2016 Source: Baylor College of Medicine Summary: Negative feedback is a universal control mechanism that lets ...

The Nature Index 2024 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their ...

This results in a read-density landscape that is biased by proximity to restriction sites (Fig. 1b), hampering identification of peaks representing DNA loop anchors and hence loops. hichipper ...

With a closed-loop optimization modality, we experimentally demonstrate effective searching for potent drug combinations for controlling cellular functions through a large parametric space.