Dutta’s study, “TRMT6/61A-dependent base methylation of tRNA-derived fragments regulates gene-silencing activity and the unfolded protein response in bladder cancer,” was recently published in Nature ...

On the basis of these results, we propose that methylation is required to protect miRNAs from AGO1-associated HESO1 activity that normally uridylates 5′ fragments. PNAS is the world's most-cited ...

A new Northwestern Medicine study has uncovered a surprising molecular link between HIV-1 and a protein fragment associated ...