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From sequence to structure: A fast track for RNA modeling
SCOPER has simplified it significantly. Say you want to study a new RNA: First, put the nucleotide sequence into one of the open-source, AI-based structure prediction tools available today.
Rachel E. Haurwitz, Martin Jinek, Blake Wiedenheft, Kaihong Zhou, Jennifer A. Doudna, Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease ...
Scientists have been unable to determine the structure of a biologically important so-called GAG proteoglycan -- or even to agree whether these remarkably complex molecules have well-defined ...
A scientist has used a form of artificial intelligence known as deep learning to predict the 3D structure of effectively any protein based on its amino acid sequence. This new approach for ...
To develop a hybrid AI pipeline that predicts three-loop G4 structures from sequence by extending AlphaFold’s sequence-to-structure functionality with a specialized deep learning model trained on ...
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