Multiple sequence alignment (MSA) is a cornerstone of computational biology, facilitating the exploration of functional, structural and evolutionary relationships among biological sequences.

For example, programs that predict constrained sequences currently assume a 'perfect' alignment and do not take into account inevitable uncertainties in the process 7.

Pectate lyases are plant virulence factors that degrade the pectate component of the plant cell wall. The enzymes share considerable sequence homology with plant pollen and style proteins, suggesting ...

On the importance of correct DNA sequence alignment in plastid phylogenomics – an example from revisiting the relationships of the water lilies Object Details Author Roestel, Jessica A. Wiersema, John ...

In an attempt to resolve alignment ambiguity and provide better scientific support for relationships, the internal transcribed spacer (ITS) of the nuclear ribosomal DNA was aligned for several gentian ...

Finding the optimal alignment between two related genomes can be difficult, though, because evolutionary distance leads to gaps and mismatches in those DNA sequences.

Application of novel alignment-free sequence descriptors in Zika virus characterization Computer-assisted approaches towards surveillance, drug design to combat Zika virus Date: April 9, 2016 ...