Covariate-adaptive randomization represents an advanced methodology in the design of clinical trials, ensuring a balanced distribution of prognostic factors among treatment groups.

The concept of randomized assignment though has long been difficult for patients and their caregivers. Use of adaptive randomization in clinical trials has emerged as a potential response to this ...

Is traditional randomization the best model for studying treatment modalities? Perhaps patient preference must be taken into account.

Community-randomized trachoma trials first suggested that azithromycin distributions decrease childhood mortality. 6,7 The MORDOR (Macrolides Oraux pour Réduire les Décès avec un Oeil sur la ...

Peer review and the editorial process yield frequent improvements in research abstracts of randomized clinical trial (RCT) ...

Randomization Techniques (60 minutes): In this workshop, the rationale behind randomized experiments will be explained. Descriptions of commonly utilized randomization algorithms will be presented, ...

In conclusion, leveraging eight phase III randomized trials, we demonstrated that when compared with NCCN risk groups, the three-tiered MMAI risk grouping system improves prognostication and has the ...

The cyclooxygenase inhibitor ibuprofen may be used to treat patent ductus arteriosus (PDA) in preterm infants. Whether selective early treatment of large PDAs with ibuprofen would improve short-term ...