Example of nonlinear regression: enzyme kinetics A prominent example of a regression equation that is nonlinear in its parameters is the Michaelis–Menten equation 64 describing enzyme kinetics.

Halbert White, Consequences and Detection of Misspecified Nonlinear Regression Models, Journal of the American Statistical Association, Vol. 76, No. 374 (Jun., 1981), pp. 419-433 ...

We propose a global smoothing method based on polynomial splines for the estimation of functional coefficient regression models for non-linear time series. Consistency and rate of convergence results ...