There is new hope for patients with a rare autoimmune disorder. In mild cases, scleroderma causes areas of hardened skin. But in severe cases, it can also cause deadly hardening of internal organs ...

Systemic sclerosis sine scleroderma (ssSSc) affects nearly 10% of patients with systemic sclerosis (SSc), with substantial internal organ involvement. Despite lacking skin fibrosis, patients with ...

Scleroderma is classified as a rare, autoimmune, collagen-vascular disease of unknown etiology that can be difficult to diagnose and treat. Its onset can be insidious or rapid; the symptoms range from ...

Sclerodactyly is a hardening of the skin of the hand that causes the fingers to curl inward and take on a claw-like shape. It is brought on by a condition called systemic scleroderma, or systemic ...

Scleroderma on the face can cause symptoms that may affect your appearance, including the texture, discoloration, and elasticity of your skin. Medications, facial exercises, and dermatological ...

A new study finds that NAD+ break down leads to multi organ scarring, providing now a previously undiscovered pathogenic role of the enzyme CD38 in disease scarring. Scleroderma, a chronic and ...

Farmington resident Sheri Hicks was a new mom living in Tucson, Ariz., when her life course changed dramatically. That painful, cracked skin on her fingertips wasn't due to overworked hands, but ...