Diagram of the structure of three theorized DNA tangles and ... In earlier work, they explored how torsional stress affects DNA replication. Nanopores give scientists a way to not only read DNA but ...

Postmitotic myotubes cannot complete DNA replication following forced cell cycle reactivation. Comparative genomic hybridization and Xenopus egg extracts show that this is primarily due to a diffuse ...

The first step in DNA replication requires the assembly of a group of proteins called the Origin Recognition Complex (ORC). Researchers have determined how the ORC assembles during the cell ...

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize ...

A new study has found that ORC plays a broad, unexpected role in regulating human cell gene expression and chromatin structure.