Despite the strong performance of Microsoft’s medical AI MAI-DxO in testing, which included models from OpenAI, Google, Anthropic, Meta, and xAI, clinical barriers remain.

MAI-DxO logged “higher diagnostic accuracy” and lower overall testing expenditure when compared to physicians or any individual foundation model. For context, the research project tested AI foundation models like ChatGPT, Llama, Claude, Gemini, Grok, and DeepSeek.

The company’s MAI-DxO system reached 85% accuracy on challenging NEJM cases, compared to 20% for doctors. The digital health market is growing, and according to Microsoft, its new AI Diagnostic Orchestrator (MAI-DxO) is among the latest in generative,