Systemic sclerosis (scleroderma) causes the body to destroy healthy tissue. It can change the appearance and texture of your skin and affect other organs. Systemic sclerosis (SS) is an autoimmune ...

A 55-year-old woman with a history of scleroderma presented after 5 days of experiencing fever, chills and progressive swelling of her right thumb (Fig. 1). The thumb was exquisitely tender to touch.

Localized scleroderma, as the term denotes, is localized to the skin on the hands and face. It is characterized by slow progression and rarely transforms to the systemic type. Localized scleroderma is ...

The management of patients with systemic sclerosis (SSc) can be challenging because disease-associated damage is often difficult to reverse and curative therapies are not yet available. Early ...

Scleroderma, also sometimes referred to as systemic sclerosis, is a chronic autoimmune disorder that involves a progressive hardening of the skin. An excess of collagen and other connective tissues in ...

Sclerodactyly is a tightening and thickening of the skin of the fingers as a result of systemic scleroderma. It can cause the fingers to curl inward and the hands to form a clawed shape. Share on ...

Dear Dr. Roach: I am a 76-year-old woman in good health, although I am overweight. I was recently diagnosed with CREST syndrome. I’m finding it difficult to learn more about this autoimmune disease.