Chief among these is accurately and reproducibly mimicking natural post-translational modifications. Identifying and characterizing such modifications impact half-life, quality, cost, and potential ...

Post-translational modifications (PTMs)—the chemical changes that proteins undergo following biosynthesis—account for most protein forms, or proteoforms. Indeed, according to conservative estimates, ...

Recent advancements in mass spectrometry and computational tools enhance the feasibility of top-down proteomics. Top-down ...

Chemical changes to histones, the proteins that help to pack and organize DNA inside cells, play a key role in determining what genes will be consistently activated over the course of an animal or ...

Tsukuba, Japan—Proteins are subject to post-translational chemical modifications that result in functional diversity. Methylation is one such modification that is generally believed to occur on lysine ...

Tuberculosis is still one of the deadliest infectious diseases, causing over one million deaths each year worldwide. Additionally, about one-fourth of the world's population carries Mycobacterium ...

Neurodegenerative diseases such as Alzheimer’s disease and related disorders, are characterized by progressive decline in cognitive function and neuronal ...

Dr. Fert-Bober is an assistant professor at Cedars-Sinai, Medical Center, Smidt Heart Institute and the Advanced Clinical Biosystems Research Institute. Dr. Fert-Bober lead a basic translational ...

Tuberculosis is a serious health threat, and the efficacy of the BCG vaccine against tuberculosis diminishes in adulthood, making booster vaccines a realistic option. Mycobacterial DNA-binding protein ...

GUILFORD, Conn.--(BUSINESS WIRE)--Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing Company™, today announced it will be presenting a poster on a new ...