Osteoporosis is a systemic skeletal disease characterized by low bone mass and deterioration of bone microarchitecture that result in bone fragility and susceptibility to fracture. 1 Positive family ...

In this lecture, the univariate twin model is extended to the bivariate twin model. It is explained how the variance in two traits is decomposed into additive genetic, non-additive genetic, and ...

Segregation analysis is a method of detecting major genes for quantitative traits without using marker information. It serves as an important tool in helping investigators to plan further studies such ...

Journal of the Royal Statistical Society. Series B (Statistical Methodology), Vol. 67, No. 1 (2005), pp. 63-78 (16 pages) The literature on multivariate linear regression includes multivariate normal ...

It can be more challenging to efficiently model the covariance matrices for multivariate longitudinal data than for the univariate case, due to the correlations arising between multiple responses. The ...

We apply distortion functions to bivariate survival functions for nonnegative random variables. This leads to a natural extension of univariate distortion risk measures to the multivariate setting.