Researchers have developed an animal model that reproduces motor dysfunction and cerebellar neurodegeneration similar to that in spinocerebellar ataxia (SCA) by inhibiting chaperone-mediated autophagy ...

Niigata, Japan – our movements are controlled by multiple neural pathways that connect the brain and spinal cord. In particular, neurons in the cerebral cortex send commands to the motor neurons in ...

Non-motor symptoms are common in Parkinson disease (PD) and can appear before motor features and progress in both severity and diversity as the disease evolves. Both dopaminergic and non-dopaminergic ...

Parkinson’s disease is a progressive disorder of later life, defined clinically by motor features (asymmetric bradykinesia, rigidity, tremor, and imbalance) and pathologically by neuronal degeneration ...

Non-invasive imaging technique called 31-phosphorus magnetic resonance spectroscopy used to measure mitochondrial function in patients with motor neuron disease (MND) Researchers from the Sheffield ...