Nearly every cell in your body depends on mitochondria to survive and function properly. Mitochondria provide 90% of our ...

Mitochondrial dysfunctions are associated with a variety of pathologies, and the onset and progression of disease are accompanied by alterations in extracellular biochemical and mechanical signals.

In 1817, a British physician named James Parkinson published An Essay on the Shaking Palsy, describing for the first time cases of a neurodegenerative disorder now known as Parkinson’s disease. Today, ...

Scientists discovered a key molecular switch to keep neurons healthy by controlling the disassembly and assembly of their ...

Many of us remember from high school biology class that mitochondria are the cell's "power plants." These small kidney-bean-shaped structures are what convert nutrients from food into ATP—the cell's ...

The tumor microenvironment (TME) is a major obstacle that limits effective cancer treatments. Various cells around the tumor promote immunosuppression and prevent the immune system from targeting ...

Chronic kidney disease (CKD) affects more than 700 million people worldwide and is caused by genetic and environmental ...

James McCully was in the lab extracting tiny structures called mitochondria from cells when researchers on his team rushed in. They’d been operating on a pig heart and couldn’t get it pumping normally ...

I always wanted to understand life. What moves us? What allows us to heal and thrive? And what goes wrong when we get sick or when we eventually stop breathing and die? My search for answers to these ...