The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

The arm extends from the shoulder to the wrist, including the upper arm and forearm. Different muscles may work together in intricate ways to help the arm, wrists, fingers, and hands function. Knowing ...