CRISPR-based tools can’t easily access the DNA in these organelles, but researchers are finding other ways in.

The discovery centers on the unique strands of DNA contained within our mitochondria, the power stations of our cells. By ...

Aging, neurological diseases and our bodies' stress response are all linked to the tiny power plants inside each cell known as mitochondria. To function properly, mitochondria must first read ...

Back in the 19 th century, as the US grappled with the aftermath of the Civil War, Jesse James, leader of a notorious gang of outlaws, rose to prominence. He robbed banks and trains for over a decade ...

Kidney damage that seemingly heals appears to mutate the DNA in the mitochondria of kidney cells, making the organ less ...

When environmental stress harms DNA, it can set off a cascade of failures linked to heart conditions, neurodegeneration, and chronic inflammation. A new chemical tool developed at UC Riverside ...

Mitochondria are widely known as the "powerhouse of the cell" because of their ability to generate energy in the body and convert nutrients from food. With such an essential job, mutations in ...

Children born to women who carry pathogenic variants in mitochondrial DNA (mtDNA) are at risk for a range of clinical syndromes collectively known as mtDNA disease. Mitochondrial donation by ...

When environmental stress harms DNA, it can set off a cascade of failures linked to heart conditions, neurodegeneration, and chronic inflammation. A new chemical tool developed at UC Riverside ...

In a step toward treating mitochondrial diseases, researchers at the University Medical Center Utrecht and their colleagues have used mitochondrial base editing (mtBE) to successfully edit harmful ...