As CRISPR continues to drive breakthroughs in medicine, agriculture, and synthetic biology, understanding its origins does more than tell an ancient story. It provides a blueprint for engineering the ...

Significant advancements in gene silencing and gene editing offer new hope for treating rare disorders. Techniques like RNA ...

Researchers at Spain’s CNIO have mapped 20,000 distinct DNA repair “scars,” building the first human REPAIRome. This atlas ...

3D visualization of the production of a red fluorescent protein in a tadpole. The gene responsible for its production is specifically activated in muscle cells. A research team headed by the ...

REPAIRome specifically addresses the repair of one of the most serious types of DNA damage, DNA double-strand breaks (DSBs).

In the late 2010s eight macaque monkeys were born at a laboratory in Shanghai. At first they seemed much like the other infants in the colony, but differences soon became obvious. They were much more ...

Investigators from Mass General Brigham and Beth Israel Deaconess Medical Center have developed STITCHR, a new gene editing tool that can insert therapeutic genes into specific locations without ...

Facioscapulohumeral Muscular Dystrophy (FSHD) is a genetic disorder marked by muscle weakness, primarily in the face, shoulders, and arms. The DUX4 gene mutation leads to toxic protein production, ...

Australian cancer researchers are the first to establish a next-generation gene-editing tool for modeling and interrogating human disease. A novel pre-clinical model expressing an enhanced version of ...