Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before ...
A hidden “jack-in-the-box” mechanism inside T cells may hold the key to unlocking more powerful cancer immunotherapies.
J. Wang et al., Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody. EMBO J. 17, 10-26 (1998). S. Rangarajan ...
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